TL;DR
- Cure vampirism within 72 hours using disease-curing items or spells
- Complete the Vampire Cure quest through Raminus Polas for full transformation cases
- Locate Cure Disease potions at alchemists or find them as random loot
- Visit chapels in Cheydinhal or Leyawiin to purchase Cure Disease spells
- Use Altar of the Nine for free curing if you maintain good reputation
While the fantasy of becoming an immortal night creature initially appeals to many players, the practical drawbacks of vampirism in Oblivion Remastered quickly become apparent. The enhanced resistances and attribute bonuses provide temporary advantages, but these benefits are substantially offset by severe sunlight penalties that limit daytime exploration and combat effectiveness. Most adventurers eventually seek to reverse this condition, whether they contracted it accidentally or through deliberate experimentation. Understanding the progression stages is crucial for effective treatment.

Vampirism treatment in Oblivion Remastered follows different pathways depending on infection duration. When engaging vampires in combat and sustaining injuries, you’ll receive a notification confirming contraction of Porphyric Hemophilia. This indicates the disease has entered your system, initiating a 72-hour countdown until complete transformation into a vampire occurs. Early detection dramatically simplifies the curing process.
If you identify the infection within the initial three-day window, reversal becomes straightforward through several accessible methods. The key is regular health monitoring after vampire encounters, as the initial symptoms can be easy to overlook during intense gameplay sessions.
During the initial infection phase, three reliable methods exist for eliminating Porphyric Hemophilia before it progresses to full vampirism. Each approach offers distinct advantages depending on your character build, current location, and available resources.

For optimal prevention, experienced players recommend maintaining at least two Cure Disease potions in your inventory at all times, especially when undertaking quests involving undead enemies. The spell variant proves most cost-effective for characters specializing in restoration magic, while the altar method suits lawful-good character alignments.
After the 72-hour transformation completes, your character becomes a full vampire, significantly complicating the curing process. The most reliable method now involves completing the specifically designed ‘Vampire Cure’ questline. Initiate this multi-stage process by traveling to the Arcane University within Imperial City’s walls and conversing with Raminus Polas, located inside the Arch-Mage Lobby structure.

Raminus will direct you to Count Hassildor in Skingrad, who requires specific ingredients for the cure potion. This typically involves collecting filled soul gems, which can be challenging during daylight hours due to vampire sunlight weaknesses. Strategic time management becomes essential for quest completion.

Successfully navigating this quest chain rewards you with the definitive Vampirism Cure Potion, permanently eliminating the condition. Many players find completing this quest during nighttime hours significantly reduces difficulty, as vampire weaknesses won’t hinder your progress.
Proactive prevention remains vastly simpler than curing advanced vampirism. When facing vampire enemies, prioritize avoiding direct melee contact whenever possible, utilizing ranged attacks or magic to minimize infection risk. Characters with high restoration skill should maintain active Cure Disease spells as standard preparation.
For comprehensive protection, consider investing in disease resistance enchantments or inherent racial traits. Wood elves and Argonians naturally possess partial disease immunity, reducing contraction probability. Additionally, regularly visiting chapels for blessing buffs provides temporary disease resistance during dangerous expeditions.
Advanced players recommend establishing a network of safe locations stocked with cure items before engaging vampire-heavy content. This strategic preparation ensures immediate treatment access if infection occurs, preventing the complicated full transformation scenario entirely.
Action Checklist
- Check disease status immediately after vampire encounters
- Use Cure Disease potion or spell within 72 hours of infection
- Visit Altar of the Nine if you maintain good reputation
- Locate Raminus Polas at Arcane University for full vampire cure
- Complete Vampire Cure quest requirements for permanent solution
No reproduction without permission:Tsp Game Club » How to Cure Vampirism in Oblivion Remastered Complete guide to curing vampirism in Oblivion Remastered with prevention strategies and quest walkthrough
